Description

3-Hydroxy-17-Aza-D-Homoandrostan-4-N,n-Bis(2-Chloroethyl)Aminophenylacetate is a complex, high-purity synthetic steroid derivative with a nitrogen mustard moiety, designed for advanced research and development applications. This compound is valued for its potential as a key intermediate or active pharmaceutical ingredient (API) in the development of targeted therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and specialty chemical manufacturers focused on oncology, endocrinology, and novel drug discovery programs.

Application

• Pharmaceutical Research Intermediate: Serves as a critical building block in the synthesis of novel steroid-based therapeutic compounds for preclinical and clinical studies.
• Oncology Drug Discovery: Investigated for its potential in developing targeted chemotherapeutic agents due to the presence of the nitrogen mustard (bis(2-chloroethyl)amino) group.
• Biochemical Tool Compound: Used in academic and industrial laboratories to study steroid receptor interactions, enzyme inhibition, and cellular signaling pathways.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis (HPLC, LC-MS).
• Specialty Chemical Synthesis: Acts as a precursor for the manufacture of more complex molecular entities in custom synthesis and contract manufacturing.

Basic Information

Product Name	3-Hydroxy-17-Aza-D-Homoandrostan-4-N,n-Bis(2-Chloroethyl)Aminophenylacetate
CAS No.	146678-51-5
Molecular Formula	C30H42Cl2N2O3
Molecular Weight	549.57 g/mol
Synonyms	4-[Bis(2-chloroethyl)amino]phenyl 3-Hydroxy-17-aza-D-homoandrostane-4-carboxylate; 17-Aza-D-homoandrostane Derivative; 3-Hydroxy-17-azaandrostane Nitrogen Mustard Ester; 146678-51-5; 4-[Bis(2-chloroethyl)amino]benzoic acid 3-hydroxy-17-aza-D-homoandrostan-4-yl ester; Mustard steroid conjugate
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-17-Aza-D-Homoandrostan-4-N,n-Bis(2-Chloroethyl)Aminophenylacetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive and potentially moisture-sensitive compound from degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.