Description

(βr)-β-Aminocyclohexanepropanoic Acid Ethyl Ester is a specialized chiral intermediate of significant importance in modern synthetic organic chemistry. Its value lies in its unique molecular architecture, featuring both a protected amino group and a cyclohexyl ring system, making it a versatile building block for complex molecule construction. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced, high-efficacy pesticides and herbicides where specific stereochemistry is required for biological activity.
• Peptidomimetics Research: Serves as a constrained, non-natural amino acid analog in the design of peptide-like molecules with enhanced metabolic stability and bioavailability.
• Catalyst and Ligand Development: Employed as a precursor for creating novel chiral catalysts and ligands used in asymmetric synthesis.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic synthesis and for exploring new chemical spaces in discovery chemistry.

Basic Information

Product Name	(βr)-β-Aminocyclohexanepropanoic Acid Ethyl Ester
CAS No.	146579-93-3
Molecular Formula	C11H21NO2
Molecular Weight	199.29 g/mol
Synonyms	Ethyl 3-((1R,2R)-2-aminocyclohexyl)propanoate; (1R,2R)-2-(2-Ethoxy-2-oxoethyl)cyclohexanamine; trans-2-(2-Ethoxy-2-oxoethyl)cyclohexanamine; (1R,2R)-2-Aminocyclohexanepropanoic Acid Ethyl Ester; (R,R)-2-(2-Ethoxycarbonylethyl)cyclohexylamine; BOC Sciences Brand Name: BBLN-0123; (1R,2R)-Ethyl 3-(2-aminocyclohexyl)propanoate
EINECS	Contact for details

Quality Control

Our (βr)-β-Aminocyclohexanepropanoic Acid Ethyl Ester is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and process development. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided and available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de (diastereomeric excess)
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.