Description

4-Bromobutyl Nitrate is a specialized organic bromide and nitrate ester compound, identified by CAS NO 146563-40-8. It serves as a valuable bifunctional building block in advanced organic synthesis, offering reactive handles for both nucleophilic substitution and nitrate ester chemistry. This chemical is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring alkyl bromide or nitrate ester functionalities.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Building Block: Employed in nucleophilic substitution reactions to introduce the 4-bromobutyl moiety into more complex molecular architectures.
• Nitrate Ester Research: Serves as a model compound or starting material in studies related to nitrate ester chemistry and energetic materials.
• Cross-Coupling Reactions: Potential substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) due to the reactive bromine atom.
• Polymer Modification: Can be used to functionalize polymers or dendrimers by reacting with nucleophilic sites on the polymer chain.

Basic Information

Product Name	4-Bromobutyl Nitrate
CAS No.	146563-40-8
Molecular Formula	C₄H₈BrNO₃
Molecular Weight	198.02 g/mol
Synonyms	1-Bromo-4-nitratobutane; Butane, 1-bromo-4-nitrooxy-; 4-Nitrato-1-bromobutane; Nitric Acid 4-Bromobutyl Ester; 4-Bromobutanol Nitrate; 4-BBN
EINECS	Contact for details

Quality Control

Our 4-Bromobutyl Nitrate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Our quality system is designed to meet the stringent requirements of GMP and ISO 9001 standards for fine chemical manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place away from heat, sparks, and open flame. Due to its light-sensitive and easily oxidized nature, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Recommended storage temperature is 2-8°C for prolonged shelf life. Keep away from strong oxidizing agents, strong bases, and reducing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.