Description

α-Propargylhomoterephthalic Acid Dimethyl Ester is a high-purity synthetic intermediate characterized by its propargyl and diester functional groups. This compound matters for its role as a versatile building block in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced materials.
• Organic Synthesis Building Block: Utilized in click chemistry (e.g., copper-catalyzed azide-alkyne cycloaddition) and other coupling reactions to create complex molecules.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological processes.
• Academic & Industrial R&D: Essential for exploratory research in synthetic methodology and new compound library generation.

Basic Information

Product Name	α-Propargylhomoterephthalic Acid Dimethyl Ester
CAS No.	146464-90-6
Molecular Formula	C14H14O4
Molecular Weight	246.26 g/mol
Synonyms	Dimethyl α-Propargylhomoterephthalate; 2-(Prop-2-yn-1-yl)benzene-1,4-dicarboxylic acid dimethyl ester; 1,4-Benzenedicarboxylic acid, 2-(2-propyn-1-yl)-, 1,4-dimethyl ester; Propargyl Homoterephthalate Dimethyl Ester; α-Propargyl-1,4-benzenedicarboxylic acid dimethyl ester; Dimethyl 2-(prop-2-yn-1-yl)terephthalate
EINECS	Contact for details

Quality Control

Our α-Propargylhomoterephthalic Acid Dimethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.