Description

Cy3 Acid(Tri So3) CAS NO 146397-18-4 is a highly functionalized, sulfonated cyanine dye derivative, a critical intermediate for advanced bioconjugation. This compound matters for its ability to impart strong, stable near-infrared fluorescence to biomolecules, enabling high-sensitivity detection and imaging. It is essential for researchers and manufacturers in the fields of biotechnology, medical diagnostics, and pharmaceutical development who require reliable, high-purity labeling reagents.

Application

• Fluorescent Labeling of Biomolecules: Covalent conjugation to proteins, antibodies, peptides, and nucleic acids (DNA/RNA) for detection assays.
• Bioimaging Probe Synthesis: Serving as a key precursor for developing near-infrared (NIR) fluorescent probes for in vitro and in vivo imaging.
• Diagnostic Kit Manufacturing: Integration into lateral flow assays (LFAs), ELISA kits, and other immunoassay platforms.
• Flow Cytometry Reagents: Creation of antibody-dye conjugates for cell sorting and analysis.
• Pharmaceutical Research: Labeling of drug candidates for pharmacokinetic and biodistribution studies.
• Material Science: Modification of polymers or nanoparticles to create fluorescent nanomaterials.

Basic Information

Product Name	Cy3 Acid(Tri So3)
CAS No.	146397-18-4
Molecular Formula	C37H41N2O13S43- • 3Na+ (or similar salt form)
Molecular Weight	~900 g/mol (Contact for exact salt form details)
Synonyms	Sulfo-Cyanine3 acid; Cyanine3 trisulfonate acid; Tri-sulfonated Cy3 NHS ester precursor; 1H-Benz[e]indolium, 2-[5-(1-carboxy-3-sulfopropyl)-2,3-dihydro-1,3-dimethyl-1H-benz[e]indol-2-ylidene]ethylidene]-5-sulfo-1,3-dihydro-3,3-dimethyl-1-(3-sulfopropyl)-, inner salt; Sulfo-Cy3 carboxylic acid; Water-soluble Cy3 acid; NIR dye acid derivative
EINECS	Contact for details

Quality Control

Our Cy3 Acid(Tri So3) is produced under strict quality management protocols to ensure batch-to-batch consistency and high performance in sensitive applications. Each lot undergoes comprehensive analytical testing including HPLC for purity, mass spectrometry (MS) for identity confirmation, and spectrophotometry to verify optical properties. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant for long-term stability. This product is hygroscopic (moisture-sensitive) and strictly light-sensitive (protect from all light exposure). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Dark green to purple solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Absorption Maximum (λmax)	548 - 552 nm
Emission Maximum	562 - 568 nm
Extinction Coefficient (ε)	≥ 150,000 cm-1M-1
Water Content (KF)	≤ 5.0 %
Solubility	Freely soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.