Description

Cy3 Diacid (Diso3) is a high-purity, functionalized cyanine dye derivative, identified by CAS No. 146397-17-3. This compound serves as a critical intermediate and labeling reagent for the synthesis of advanced fluorescent probes and bioconjugates. It is essential for researchers and manufacturers in the life sciences, diagnostics, and pharmaceutical development sectors who require reliable, high-performance materials for sensitive detection and imaging applications.

Application

• Fluorescent Labeling Reagent: Primary use as an active ester precursor for covalently labeling biomolecules such as proteins, peptides, antibodies, and nucleic acids.
• Bioconjugate Synthesis: Key building block for creating targeted imaging agents and therapeutic-diagnostic (theranostic) conjugates.
• Probe and Sensor Development: Used in the design and manufacture of fluorescent probes for in vitro and in vivo imaging, including near-infrared (NIR) applications.
• Diagnostic Assays: Integral component in the production of reagents for fluorescence-based immunoassays, flow cytometry, and microscopy.
• Material Science: Functional dye for incorporation into polymers and nanoparticles to create advanced functional materials with optical properties.
• Research & Development: A vital tool in academic and industrial R&D for studying biomolecular interactions, cellular processes, and drug delivery mechanisms.

Basic Information

Product Name	Cy3 Diacid (Diso3)
CAS No.	146397-17-3
Molecular Formula	C37H41N2O8S2+ • 2X- (X = counterion)
Molecular Weight	Contact for details
Synonyms	Sulfo-Cyanine3 diacid; Disulfo-Cyanine3 carboxylic acid; Cy3™ disulfonated diacid; 1,1'-(3,3',3''-(1E,1'E)-(Cycloprop-1-ene-1,3-diyl)bis(prop-1-ene-3,1-diyl))bis(3,3-dimethyl-5-sulfo-1-(3-sulfopropyl)indol-1-ium-2-yl)diacetate; Cy3 bis-sulfonated NHS ester precursor; Fluorescent cyanine dye diacid derivative; ICG derivative diacid; Near-infrared dye intermediate.
EINECS	Contact for details

Quality Control

Our Cy3 Diacid (Diso3) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive bioconjugation and research applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and performance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity. For long-term storage, consider desiccant use.

Specification

Item	Specification
Appearance	Dark green to purple solid
Identification (HPLC)	Conforms to reference standard
Identification (UV-Vis)	λmax conforms
Purity (HPLC)	≥ 95% (Area %)
Single Largest Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.