Description

2-[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]Acetic Acid Methyl Ester is a specialized organosilicon-protected glycolic acid derivative, serving as a crucial synthetic intermediate in advanced organic chemistry. This compound is valued for its role in introducing protected hydroxyacetate moieties, enabling complex multi-step syntheses under controlled conditions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the production of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules, particularly those requiring protected glycolic acid or hydroxyacetate functional groups.
• Peptide Mimetics & Modifications: Used to incorporate silyl-protected hydroxyacetic acid units into peptide chains for structure-activity relationship (SAR) studies.
• Agrochemical Synthesis: Intermediate in the production of advanced herbicides, fungicides, and plant growth regulators.
• Polymer & Material Science: Monomer or co-monomer for creating specialty polymers with tailored properties, such as biodegradable materials or functional coatings.
• Linker Chemistry: Employed in solid-phase synthesis and bioconjugation strategies where a cleavable or stable linker is required.
• Academic & Contract Research: Essential reagent for methodological development and exploratory synthesis in university and CRO laboratories.

Basic Information

Product Name	2-[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]Acetic Acid Methyl Ester
CAS No.	146351-72-6
Molecular Formula	C9H20O3Si
Molecular Weight	204.34 g/mol
Synonyms	Methyl (tert-Butyldimethylsilyloxy)acetate; Methyl [(tert-Butyldimethylsilyl)oxy]acetate; Methyl 2-[(tert-Butyldimethylsilyl)oxy]acetate; TBDMS-Glycolic Acid Methyl Ester; (tert-Butyldimethylsiloxy)acetic Acid Methyl Ester; 2-(tert-Butyldimethylsiloxy)acetic Acid Methyl Ester; Glycolic Acid Methyl Ester TBDMS Ether; Acetic acid, 2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-, methyl ester
EINECS	Contact for details

Quality Control

Our 2-[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]Acetic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. The container should be kept tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.