Description

Cyclopropanecarboxylic Acid, 2-(1,2-Dihydroxyethyl)-, Methyl Ester is a specialized chiral building block and synthetic intermediate of significant interest in advanced organic synthesis. This compound, with CAS NO 146144-30-1, is valued for its unique cyclopropane ring fused with a dihydroxyethyl side chain, offering a rigid, strained framework for constructing complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new drug candidates, particularly in antiviral, anticancer, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the cyclopropane moiety can enhance biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or cross-linking agent for producing polymers with unique thermal and mechanical properties.
• Academic & Contract Research: Essential reagent for methodological studies in organic chemistry, including ring-opening and functionalization reactions.
• Flavor & Fragrance Industry: Potential intermediate for synthesizing complex, naturally-derived odorants and flavor compounds.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 2-(1,2-Dihydroxyethyl)-, Methyl Ester
CAS No.	146144-30-1
Molecular Formula	C8H14O5
Molecular Weight	190.19 g/mol
Synonyms	Methyl 2-(1,2-dihydroxyethyl)cyclopropanecarboxylate; (1R,2S)-rel-2-(1,2-Dihydroxyethyl)cyclopropanecarboxylic Acid Methyl Ester; Methyl (1R,2S)-2-(1,2-dihydroxyethyl)cyclopropanecarboxylate; Cyclopropanecarboxylic acid, 2-(1,2-dihydroxyethyl)-, methyl ester, (1R,2S)-rel-; Methyl 2-(1,2-dihydroxyethyl)cyclopropanecarboxylate (racemic); Dihydroxyethyl cyclopropanecarboxylate methyl ester
EINECS	Contact for details

Quality Control

Our production of Cyclopropanecarboxylic Acid, 2-(1,2-Dihydroxyethyl)-, Methyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and scale-up applications. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess (where applicable), and impurity profile is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	Contact for details (racemic or chiral grades available)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.