Description

5-Iodo-Benzo[B]Thiophene-2-Carboxylic Acid Methyl Ester is a high-purity, specialized organic building block of significant interest in advanced chemical synthesis. This compound matters as a key intermediate for constructing complex heterocyclic molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the benzothiophene core.
• Material Science Precursor: Acts as a monomer or functionalizing agent in the creation of organic semiconductors, conductive polymers, and advanced organic electronic materials.
• Chemical Biology Probe Synthesis: Utilized to create labeled compounds or molecular probes for studying biological pathways and protein interactions.
• Ligand and Catalyst Development: Provides a functionalized scaffold for constructing complex ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules on a commercial scale.

Basic Information

Product Name	5-Iodo-Benzo[B]Thiophene-2-Carboxylic Acid Methyl Ester
CAS No.	146137-90-8
Molecular Formula	C10H7IO2S
Molecular Weight	318.13 g/mol
Synonyms	Methyl 5-iodobenzo[b]thiophene-2-carboxylate; 5-Iodobenzo[b]thiophene-2-carboxylic acid methyl ester; 2-Methoxycarbonyl-5-iodobenzo[b]thiophene; Benzo[b]thiophene-2-carboxylic acid, 5-iodo-, methyl ester; 5-Iodo-1-benzothiophene-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 5-Iodo-Benzo[B]Thiophene-2-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality supports compliance in cGMP (current Good Manufacturing Practice) environments for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be amber-colored or stored in opaque secondary packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.