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(2R,3R)-2,3-Bis(Phenylcarbamoyloxy) Succinic Acid CAS NO 145943-92-6


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CAS No.:145943-92-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(2R,3R)-2,3-Bis(Phenylcarbamoyloxy) Succinic Acid is a chiral, multifunctional organic acid derivative of significant interest in advanced chemical synthesis. This compound matters as a high-value building block or chiral auxiliary for creating stereochemically defined molecules in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), asymmetric catalysts, and specialty fine chemicals.

Application

  • Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of complex drug molecules, particularly those requiring specific (2R,3R) stereochemistry.
  • Asymmetric Catalyst Ligand Precursor: Used to develop novel ligands for metal-catalyzed reactions where high enantioselectivity is critical.
  • Agrochemical Research: Employed in the development of new, stereospecific pesticides and herbicides.
  • Polymer Modification: Acts as a functional monomer or cross-linking agent for creating specialty polymers with tailored properties.
  • Academic & Industrial R&D: A valuable tool compound for methodological studies in organic synthesis and stereochemistry.
  • Fine Chemical Production: Used in the custom synthesis of other high-value, optically active compounds for various industrial applications.

Basic Information

Product Name (2R,3R)-2,3-Bis(Phenylcarbamoyloxy) Succinic Acid
CAS No. 145943-92-6
Molecular Formula C18H16N2O8
Molecular Weight 388.33 g/mol
Synonyms (2R,3R)-2,3-Bis(phenylcarbamoyloxy)butanedioic acid; (2R,3R)-2,3-Di(phenylcarbamoyloxy)succinic acid; L-Tartaric acid bis(phenylurethane); (R,R)-O,O'-Bis(phenylcarbamoyl)tartaric acid; (2R,3R)-Tartaric acid bis(N-phenylcarbamate); (R,R)-Tartaric acid diphenyl diamide derivative; Contact for additional trade names and abbreviations.
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Quality Control

Our (2R,3R)-2,3-Bis(Phenylcarbamoyloxy) Succinic Acid is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles. We adhere to cGMP principles where applicable to support its use in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Chiral Purity (HPLC) ≥ 99.0% ee (2R,3R)
Loss on Drying ≤ 1.0%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 20 ppm
Single Unknown Impurity (HPLC) ≤ 0.5%
Total Impurities (HPLC) ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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