Description

Cerivastatin Sodium is a synthetic, highly potent HMG-CoA reductase inhibitor belonging to the statin class of pharmaceuticals. Its primary value lies in its role as a critical pharmaceutical intermediate and reference standard for research and development. This compound is essential for manufacturers and research institutions focused on cardiovascular disease, lipid metabolism studies, and analytical method development. The material is supplied under strict quality control to ensure consistency for sensitive applications.

Application

• Pharmaceutical Intermediate: Key starting material (KSM) or advanced intermediate in the synthesis of cerivastatin and related statin analogs.
• Reference Standard: Certified reference material (CRM) for quality control (QC) and quality assurance (QA) in pharmaceutical manufacturing.
• Analytical Research: Used as a standard in High-Performance Liquid Chromatography (HPLC), Mass Spectrometry (MS), and other analytical methods for quantification and identification.
• Biochemical Research: Tool compound for in-vitro studies investigating HMG-CoA reductase inhibition, cholesterol biosynthesis pathways, and cellular lipid metabolism.
• Metabolite Studies: Used in the research and synthesis of drug metabolites for pharmacokinetic and pharmacodynamic profiling.

Basic Information

Product Name	Cerivastatin Sodium
CAS No.	145599-86-6
Molecular Formula	C26H33FNO5•Na
Molecular Weight	481.54 g/mol
Synonyms	Cerivastatin Sodium Salt; (+)-Cerivastatin Sodium; (3R,5S)-Cerivastatin Sodium; Rivastatin Sodium; BAY w 6228; BAY-w 6228; BAYw6228; (E)-(3R,5S)-7-[4-(4-Fluorophenyl)-2,6-diisopropyl-5-methoxymethyl-pyridin-3-yl]-3,5-dihydroxy-hept-6-enoic Acid Sodium Salt
EINECS	Contact for details

Quality Control

Our Cerivastatin Sodium is manufactured under a GMP-compliant quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing results for assay, related substances, residual solvents, and other critical parameters. We support compliance with major pharmacopoeial standards, including USP and EP, upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Water Content (KF)	≤5.0%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.