Description

Trifluoroacetyltriphenylsilane 2,4,6-Triisopropylbenzenesulfonylhydrazone is a specialized organosilicon reagent featuring a unique trifluoroacetyl hydrazone functional group. This compound is valued for its role as a key intermediate in advanced organic synthesis, particularly in the construction of complex molecules and fluorinated compounds. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications requiring precise molecular transformations.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those incorporating fluorine atoms for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and pesticides where the fluorinated moiety can improve efficacy and environmental profile.
• Advanced Material Precursor: Acts as a precursor in the development of specialty polymers, liquid crystals, and organic electronic materials that benefit from silicon and fluorine incorporation.
• Cross-Coupling & Functionalization Reagent: Employed in palladium-catalyzed cross-coupling reactions and other metal-mediated transformations to introduce specific functional groups.
• Laboratory Research: A valuable tool for academic and industrial R&D in methodology development for C–N and C–Si bond formation.
• Fluorine Chemistry: Essential for exploring new pathways in fluoroorganic chemistry, enabling the introduction of the trifluoroacetyl group into complex scaffolds.

Basic Information

Product Name	Trifluoroacetyltriphenylsilane 2,4,6-Triisopropylbenzenesulfonylhydrazone
CAS No.	145574-05-6
Molecular Formula	C31H34F3N2O3SSi
Molecular Weight	608.76 g/mol
Synonyms	Trifluoroacetyltriphenylsilane 2,4,6-Triisopropylbenzenesulfonyl Hydrazone; (Triphenylsilyl)(2,4,6-triisopropylbenzenesulfonyl)hydrazono(trifluoro)methane; Trifluoroacetyltriphenylsilane Tosylhydrazone Analog; TFTS-Trisyl Hydrazone; Silane, trifluoroacetyltriphenyl-, 2,4,6-triisopropylbenzenesulfonylhydrazone; CAS 145574-05-6
EINECS	Contact for details

Quality Control

Our Trifluoroacetyltriphenylsilane 2,4,6-Triisopropylbenzenesulfonylhydrazone is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. We adhere to strict quality management protocols to meet the exacting standards of research and process chemistry applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.