Description

(10S,13R,14S,17R)-4,4,10,13-Tetramethyl-17-[(2R)-6-Methylhept-5-En-2-Yl]-3-Oxo-1,2,5,6,7,11,12,15,16,17-Decahydrocyclopenta[A]Phenanthrene-14-Carboxylic Acid CAS NO 145525-33-3 is a high-purity, steroidal carboxylic acid derivative of significant interest in advanced pharmaceutical research and synthesis. This compound serves as a critical chiral intermediate for the development of novel therapeutic agents, particularly in the fields of endocrinology and metabolic disease. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries who require structurally complex and stereochemically defined building blocks.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel steroid-based drugs and hormone analogs.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and biological target validation.
• Process Chemistry: Serves as a starting material or advanced intermediate in the scale-up and optimization of API (Active Pharmaceutical Ingredient) manufacturing routes.
• Biochemical Research: Potential tool compound for studying steroid receptor interactions and metabolic pathways in academic and industrial labs.
• Fine Chemical Synthesis: Building block for creating specialized libraries of complex organic molecules for high-throughput screening.

Basic Information

Item	Details
Product Name	(10S,13R,14S,17R)-4,4,10,13-Tetramethyl-17-[(2R)-6-Methylhept-5-En-2-Yl]-3-Oxo-1,2,5,6,7,11,12,15,16,17-Decahydrocyclopenta[A]Phenanthrene-14-Carboxylic Acid
CAS No.	145525-33-3
Molecular Formula	C30H44O3
Molecular Weight	452.67 g/mol
Synonyms	3-Oxo-24-norchola-4,22-diene-23-carboxylic acid; (22E)-3-Oxochola-4,22-dien-24-oic acid; 3-Oxochola-4,22-dien-24-oic acid; Steroid carboxylic acid intermediate; Chiral steroidal acid; 24-Norchola-4,22-diene-23-carboxylic acid, 3-oxo-; (22E)-3-Oxo-24-norchola-4,22-dien-23-oic acid
EINECS	Contact for details

Quality Control

Our (10S,13R,14S,17R)-4,4,10,13-Tetramethyl-17-[(2R)-6-Methylhept-5-En-2-Yl]-3-Oxo-1,2,5,6,7,11,12,15,16,17-Decahydrocyclopenta[A]Phenanthrene-14-Carboxylic Acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure identity, strength, quality, and purity. Certificates of Analysis (COA) documenting all critical parameters are provided and available upon request to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.