Description

n-Acetyl-L-Cysteine Allyl Ester is a specialized derivative of the amino acid L-cysteine, featuring both an acetyl-protected thiol group and a reactive allyl ester moiety. This unique bifunctional structure makes it a valuable intermediate for synthesizing complex molecules, particularly in pharmaceutical research and development. It is primarily utilized by researchers and manufacturers in the life sciences sector for applications ranging from drug discovery to the development of novel therapeutic agents and biochemical tools.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly those targeting oxidative stress or requiring thiol-based prodrug strategies.
• Bioconjugation & Peptide Chemistry: The allyl ester group serves as a versatile handle for coupling reactions, useful in peptide synthesis and the creation of protein conjugates or labeled biomolecules.
• Research Chemical: Employed in academic and industrial R&D laboratories for studying thiol-disulfide exchange mechanisms and developing new biochemical probes.
• Prodrug Development: Utilized in the design of prodrugs where the acetyl and allyl ester groups can be cleaved enzymatically or chemically to release the active L-cysteine moiety.
• Cross-linking Agent: The reactive functional groups allow it to act as a cross-linker in polymer chemistry or material science for creating specialized biomaterials.

Basic Information

Product Name	n-Acetyl-L-Cysteine Allyl Ester
CAS No.	145452-04-6
Molecular Formula	C8H13NO3S
Molecular Weight	203.26 g/mol
Synonyms	N-Acetyl-L-cysteine allyl ester; N-Acetylcysteine allyl ester; Allyl N-acetyl-L-cysteinate; L-Cysteine, N-acetyl-, allyl ester; (R)-2-(Acetylamino)-3-(allyloxy)-3-oxopropane-1-thiol; NAC-Allyl Ester; S-Acetylcysteine allyl ester (common misnomer); 2-Acetamido-3-(allyloxy)-3-thioxopropanoic acid (related form)
EINECS	Contact for details

Quality Control

Our n-Acetyl-L-Cysteine Allyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. The material is light-sensitive and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.