Description

(2R,4S)-n-Benzyl-2-T-Butyloxazolidine-4-Carboxylic Acid, Methyl Ester is a high-purity, chiral oxazolidine derivative that serves as a critical synthetic intermediate. This compound is valued for its role in the stereoselective synthesis of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical industries for applications in asymmetric synthesis and chiral auxiliary chemistry.

Application

• Chiral Auxiliary in Asymmetric Synthesis: Used to induce stereoselectivity in the formation of new chiral centers during complex organic reactions.
• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of enantiomerically pure drug candidates and active pharmaceutical ingredients (APIs).
• Peptidomimetic Research: Employed in the design and synthesis of peptide analogs and conformationally restricted scaffolds for drug discovery.
• Catalyst and Ligand Preparation: Serves as a precursor for the synthesis of specialized chiral catalysts and ligands used in homogeneous catalysis.
• Academic and R&D Laboratories: Utilized in methodological development and exploratory chemistry for creating novel chiral compounds.
• Fine Chemical Production: Integrated into the manufacture of high-value, specialty chemicals requiring specific stereochemistry.

Basic Information

Product Name	(2R,4S)-n-Benzyl-2-T-Butyloxazolidine-4-Carboxylic Acid, Methyl Ester
CAS No.	145451-89-4
Molecular Formula	C16H23NO3
Molecular Weight	277.36 g/mol
Synonyms	(2R,4S)-N-Benzyl-2-(tert-Butyl)-1,3-oxazolidine-4-carboxylic Acid Methyl Ester; Methyl (2R,4S)-N-Benzyl-2-(tert-butyl)-1,3-oxazolidine-4-carboxylate; (2R,4S)-N-Benzyl-2-tert-Butyloxazolidine-4-carboxylic Acid Methyl Ester; (2R-cis)-N-Benzyl-2-(1,1-Dimethylethyl)-4-oxazolidinecarboxylic Acid Methyl Ester; N-Benzyl-2-tert-butyl-(4S,2R)-oxazolidine-4-carboxylic Acid Methyl Ester; Chiral Oxazolidine Ester; Benzyl-tert-butyl-oxazolidine Methyl Ester
EINECS	Contact for details

Quality Control

Our (2R,4S)-n-Benzyl-2-T-Butyloxazolidine-4-Carboxylic Acid, Methyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and enantiomeric excess meet the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing specific results for chiral purity (HPLC), assay, and related substances are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.