Description

1,3,5-Tri-o-Benzoyl-2-Deoxyribofuranose is a key benzoylated nucleoside derivative, serving as a crucial protected intermediate in synthetic organic chemistry. Its primary value lies in enabling the controlled synthesis of modified nucleosides and oligonucleotides, where selective deprotection is required. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly those developing antiviral agents, anticancer drugs, and advanced nucleic acid-based therapeutics.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel nucleoside analogs for antiviral and anticancer drug discovery.
• Oligonucleotide Synthesis: Used as a protected monomer for the solid-phase or solution-phase synthesis of modified DNA/RNA strands.
• Prodrug Development: Employed in creating prodrug forms of nucleoside therapeutics to enhance bioavailability and targeting.
• Chemical Biology Research: A valuable tool for studying enzyme mechanisms and metabolic pathways involving nucleosides.
• Process Chemistry: Serves as a high-purity intermediate in the scaled-up manufacturing of active pharmaceutical ingredients (APIs).
• Academic & R&D Laboratories: Used in methodological development and as a reference standard in analytical studies.

Basic Information

Product Name	1,3,5-Tri-o-Benzoyl-2-Deoxyribofuranose
CAS No.	145416-96-2
Molecular Formula	C26H22O7
Molecular Weight	446.45 g/mol
Synonyms	1,3,5-Tri-O-benzoyl-2-deoxy-D-ribofuranose; 2-Deoxy-1,3,5-tri-O-benzoyl-D-ribofuranose; 2-Deoxyribofuranose, 1,3,5-tribenzoate; 1,3,5-Tri-O-benzoyl-2-deoxy-D-erythro-pentofuranose; Tribenzoyl-2-deoxyribofuranose; 2-Deoxy-1,3,5-tris-O-(phenylcarbonyl)-D-ribofuranose; D-2-Deoxyribose 1,3,5-tribenzoate
EINECS	Contact for details

Quality Control

Our 1,3,5-Tri-o-Benzoyl-2-Deoxyribofuranose is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP-grade requirements. Specifications can be tailored to meet specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider inert atmosphere packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.