Description

5-Oxa-2-Aza-Spiro[3.4]Octane is a versatile and high-value spirocyclic building block in organic synthesis. This heterocyclic compound is prized for its unique three-dimensional structure, which is crucial for modulating the physicochemical properties and biological activity of advanced molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the discovery and optimization of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key scaffold in the synthesis of drug candidates targeting central nervous system (CNS) disorders, infectious diseases, and metabolic conditions.
• Agrochemical Research: Used as a core structure for developing new herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Chemical Biology Probe: Serves as a privileged fragment in fragment-based drug discovery (FBDD) and for constructing molecular probes to study biological pathways.
• Material Science Precursor: Employed in the research and development of advanced polymers and functional materials with specific thermal or mechanical properties.
• Custom Synthesis Building Block: Supplied to contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects requiring complex spirocyclic architectures.

Basic Information

Product Name	5-Oxa-2-Aza-Spiro[3.4]Octane
CAS No.	145309-24-6
Molecular Formula	C6H9NO
Molecular Weight	111.14 g/mol
Synonyms	2-Aza-5-oxaspiro[3.4]octane; 5-Oxa-2-azaspiro[3.4]octane; Spiro[3.4]octane, 5-oxa-2-aza-; 1-Oxa-4-azaspiro[2.4]heptane (tautomeric form); Oxazaspirooctane; Azaspirocyclic ether
EINECS	Contact for details

Quality Control

Our 5-Oxa-2-Aza-Spiro[3.4]Octane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications in GMP and ISO-regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.