Description

2-Azabicyclo[3.1.0]Hexane-1-Carboxylicacid,Methylester,(1S)-(9Ci) CAS NO 145241-93-6 is a high-purity, chiral bicyclic proline derivative, serving as a critical building block in advanced organic synthesis. Its unique constrained ring structure and defined stereochemistry make it an invaluable scaffold for constructing complex molecules with precise three-dimensional architecture. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and chiral catalysts.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Agrochemical Synthesis: Used in the creation of novel, stereospecific pesticides and herbicides with enhanced efficacy and environmental profiles.
• Catalyst Ligand Precursor: Serves as a starting material for the synthesis of sophisticated chiral ligands used in asymmetric catalysis.
• Peptidomimetics & Constrained Peptides: Incorporated into peptide backbones to induce specific conformational restraints, improving metabolic stability and biological activity.
• Academic & Institutional Research: Employed in methodological studies and the exploration of new synthetic routes involving strained heterocyclic systems.
• Custom Synthesis & Contract Manufacturing: A requested intermediate for bespoke chemical manufacturing services (CMS) targeting complex, high-value molecules.

Basic Information

Product Name	2-Azabicyclo[3.1.0]Hexane-1-Carboxylicacid,Methylester,(1S)-(9Ci)
CAS No.	145241-93-6
Molecular Formula	C7H11NO2
Molecular Weight	141.17 g/mol
Synonyms	(1S)-2-Azabicyclo[3.1.0]hexane-1-carboxylic acid methyl ester; Methyl (1S)-2-azabicyclo[3.1.0]hexane-1-carboxylate; (1S)-Methyl 2-azabicyclo[3.1.0]hexane-1-carboxylate; (1S,5S)-Methyl 2-azabicyclo[3.1.0]hexane-1-carboxylate; L-2-Azabicyclo[3.1.0]hexane-1-carboxylic acid methyl ester; Bicyclic proline methyl ester; CAS 145241-93-6
EINECS	Contact for details

Quality Control

Our 2-Azabicyclo[3.1.0]Hexane-1-Carboxylicacid,Methylester,(1S)-(9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if opened for prolonged use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.