Description

Cyclopropanecarboxylic Acid, 2-Ethoxy-3-Methyl-, 1,1-Dimethylethyl Ester, (1Alpha,2Ba,3Alpha)- (9Ci) is a high-purity, stereochemically defined cyclopropane derivative serving as a critical chiral building block in advanced organic synthesis. Its value lies in providing a rigid, three-membered ring scaffold with specific stereochemistry and functional handles, enabling the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients where precise spatial orientation is crucial for biological activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in therapeutic areas targeting the central nervous system, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the cyclopropane ring contributes to stability and bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or additive for creating polymers with unique thermal and mechanical properties due to the strained ring structure.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes to study enzyme mechanisms and biological pathways.
• Flavor and Fragrance Chemistry: Potential intermediate for synthesizing complex aroma compounds with specific stereochemical notes.

Basic Information

Item	Detail
Product Name	Cyclopropanecarboxylic Acid, 2-Ethoxy-3-Methyl-, 1,1-Dimethylethyl Ester, (1Alpha,2Ba,3Alpha)- (9Ci)
CAS No.	145164-87-0
Molecular Formula	C12H22O3
Molecular Weight	214.30 g/mol
Synonyms	(1α,2β,3α)-2-Ethoxy-3-methylcyclopropanecarboxylic acid tert-butyl ester; tert-Butyl (1α,2β,3α)-2-ethoxy-3-methylcyclopropanecarboxylate; (1R,2S,3R)-2-Ethoxy-3-methylcyclopropanecarboxylic acid 1,1-dimethylethyl ester; (1Alpha,2Ba,3Alpha)-2-Ethoxy-3-methylcyclopropanecarboxylic acid tert-butyl ester; tert-Butyl (1R,2S,3R)-2-ethoxy-3-methylcyclopropanecarboxylate; 145164-87-0; Cyclopropanecarboxylic acid, 2-ethoxy-3-methyl-, 1,1-dimethylethyl ester, (1α,2β,3α)-
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 2-Ethoxy-3-Methyl-, 1,1-Dimethylethyl Ester, (1Alpha,2Ba,3Alpha)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure high chemical and stereochemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.