Description

6,9-Diaza-Spiro[4.5]Decane Dihydrochloride is a high-purity, versatile organic building block and pharmaceutical intermediate. This compound is valued for its rigid, three-dimensional spirocyclic structure, which is crucial for modulating the physicochemical properties and biological activity of drug candidates. It is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the development of novel therapeutics targeting the central nervous system and other disease areas.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug molecules, especially those requiring a constrained, bicyclic amine scaffold.
• Medicinal Chemistry Research: Used as a versatile building block for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Ligand Synthesis: Employed in the development of chelating agents, catalysts, and ligands for coordination chemistry and catalysis.
• Chemical Biology Probes: Serves as a core structure for developing molecular probes to study enzyme function and biological pathways.
• Agrochemical Research: Potential intermediate in the research and development of new active ingredients for crop protection.
• Academic & Industrial R&D: Fundamental research chemical for exploring new synthetic methodologies and novel chemical entities.

Basic Information

Product Name	6,9-Diaza-Spiro[4.5]Decane Dihydrochloride
CAS No.	145122-55-0
Molecular Formula	C8H18Cl2N2
Molecular Weight	213.15 g/mol
Synonyms	6,9-Diazaspiro[4.5]decane dihydrochloride; 1,4-Diazaspiro[4.5]decane dihydrochloride; Spiro[4.5]decane-6,9-diamine dihydrochloride; 6,9-Diazaspiro[4.5]decane, hydrochloride (1:2); 6,9-Diaza-spiro[4.5]decane HCl; 6,9-Diaza-spiro[4.5]decane dihydrochloride salt
EINECS	Contact for details

Quality Control

Our 6,9-Diaza-Spiro[4.5]Decane Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.