Description

2,5-Piperidinedicarboxylic Acid, 1-[2-(1,3-Dihydro-1,3-Dioxo-2H-Isoindol-2-Yl)Ethyl]-, 2,5-Dimethyl Ester, (2R,5S)-Rel- is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. This compound matters as a sophisticated intermediate, enabling the construction of complex molecular architectures with precise stereochemical control. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder therapeutics.
• Agrochemical Synthesis: Used in the creation of advanced, stereoselective pesticides and herbicides where specific chirality impacts biological activity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for the synthesis of novel chiral ligands and organocatalysts.
• Peptidomimetic Research: Employed in the design and synthesis of peptide analogs and conformationally constrained scaffolds for drug discovery.
• Academic & Contract Research: A valuable tool for methodological development in organic chemistry and stereoselective synthesis at universities and CROs.
• Fine Chemical Production: Intermediate in the multi-step synthesis of specialty chemicals and advanced materials.

Basic Information

Product Name	2,5-Piperidinedicarboxylic Acid, 1-[2-(1,3-Dihydro-1,3-Dioxo-2H-Isoindol-2-Yl)Ethyl]-, 2,5-Dimethyl Ester, (2R,5S)-Rel-
CAS No.	145011-61-6
Molecular Formula	C20H24N2O6
Molecular Weight	388.42 g/mol
Synonyms	rel-(2R,5S)-1-[2-(1,3-Dioxoisoindolin-2-yl)ethyl]-2,5-dimethyl piperidine-2,5-dicarboxylate; (2R,5S)-1-(2-Phtalimidoethyl)-2,5-dimethyl piperidine-2,5-dicarboxylate; 1-(2-Phtalimidoethyl)-2,5-dimethyl piperidine-2,5-dicarboxylate (rel-(2R,5S)-); Piperidine-2,5-dicarboxylic acid, 1-[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)ethyl]-, 2,5-dimethyl ester, (2R,5S)-rel-; CAS 145011-61-6
EINECS	Contact for details

Quality Control

Our 2,5-Piperidinedicarboxylic Acid, 1-[2-(1,3-Dihydro-1,3-Dioxo-2H-Isoindol-2-Yl)Ethyl]-, 2,5-Dimethyl Ester, (2R,5S)-Rel- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and stereochemical purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.