Description

Resiquimod is a potent synthetic immune response modifier belonging to the imidazoquinoline amine family. This compound is of significant commercial and research interest due to its role as a toll-like receptor 7 (TLR7) and TLR8 agonist, stimulating innate and adaptive immune responses. It is primarily utilized in the pharmaceutical and biotechnology sectors for the development of novel immunotherapies and vaccine adjuvants. Resiquimod CAS NO 144875-48-9 represents a high-value active pharmaceutical ingredient (API) for advanced therapeutic applications.

Application

• Development of topical immunomodulatory treatments for viral skin infections (e.g., herpes, HPV) and certain dermatological cancers.
• Research and formulation of vaccine adjuvants to enhance the efficacy of prophylactic and therapeutic vaccines.
• Pre-clinical and clinical studies targeting oncology immunotherapies, including combination therapies.
• Investigation of antiviral agents due to its ability to induce interferon and other cytokine production.
• Use as a reference standard in analytical laboratories for quality control and method development.
• Component in pharmaceutical intermediates for the synthesis of more complex immunomodulatory compounds.

Basic Information

Item	Details
Product Name	Resiquidmod
CAS No.	144875-48-9
Molecular Formula	C17H22N4O2
Molecular Weight	314.38 g/mol
Synonyms	R-848; S-28463; 4-Amino-2-(ethoxymethyl)-α,α-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol; 1-(4-Amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol; Resiquimodum; TLR7/8 Agonist R848
EINECS	Contact for details

Quality Control

Our Resiquimod is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant ICH guidelines, and our quality control protocols are designed to meet the stringent requirements for active pharmaceutical ingredients (APIs). Certificates of Analysis are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.