Description

Methyl 2-Aminosulfonyl-6-(Trifluoromethyl)Pyridine-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its pyridine core with sulfonamide and trifluoromethyl substituents. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing next-generation compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, especially those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new herbicides and pesticides, where the trifluoromethyl and sulfonamide groups contribute to biological activity and environmental stability.
• Chemical Synthesis Building Block: Employed in organic synthesis for constructing functionalized pyridine derivatives in academic and industrial R&D settings.
• Material Science Applications: Potential use in the development of specialty chemicals and functional materials due to its unique electronic properties.

Basic Information

Product Name	Methyl 2-Aminosulfonyl-6-(Trifluoromethyl)Pyridine-3-Carboxylate
CAS No.	144740-59-0
Molecular Formula	C8H7F3N2O4S
Molecular Weight	284.21 g/mol
Synonyms	Methyl 2-(Aminosulfonyl)-6-(trifluoromethyl)nicotinate; 2-Aminosulfonyl-6-trifluoromethyl-nicotinic acid methyl ester; 6-(Trifluoromethyl)-2-sulfamoyl-nicotinic acid methyl ester; Methyl 6-(trifluoromethyl)-2-sulfamoylpyridine-3-carboxylate; 3-Pyridinecarboxylic acid, 2-(aminosulfonyl)-6-(trifluoromethyl)-, methyl ester; 144740-59-0; Methyl 2-sulfamoyl-6-(trifluoromethyl)nicotinate
EINECS	Contact for details

Quality Control

Our Methyl 2-Aminosulfonyl-6-(Trifluoromethyl)Pyridine-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is moisture-sensitive (hygroscopic) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.