Description

Methyl 2-Oxo-6-(Trifluoromethyl)-1,2-Dihydropyridine-3-Carboxylate is a high-value, fluorinated heterocyclic building block essential for advanced organic synthesis. This compound matters because its unique trifluoromethyl-substituted dihydropyridone core serves as a versatile precursor for developing novel pharmaceuticals and agrochemicals with enhanced metabolic stability and bioavailability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group improves lipophilicity and biological activity.
• Chemical Research & Development: Serves as a critical scaffold in organic synthesis for constructing complex nitrogen-containing heterocycles and fluorinated compounds.
• Material Science Precursor: Potential application in the synthesis of specialty polymers, ligands for catalysis, and advanced organic electronic materials.

Basic Information

Product Name	Methyl 2-Oxo-6-(Trifluoromethyl)-1,2-Dihydropyridine-3-Carboxylate
CAS No.	144740-55-6
Molecular Formula	C8H6F3NO3
Molecular Weight	221.13 g/mol
Synonyms	Methyl 6-(trifluoromethyl)-2-oxo-1,2-dihydropyridine-3-carboxylate; 3-Carbomethoxy-6-(trifluoromethyl)-2-pyridone; 6-(Trifluoromethyl)-1,2-dihydro-2-oxo-3-pyridinecarboxylic acid methyl ester; Methyl 6-(trifluoromethyl)-2-oxo-1H-pyridine-3-carboxylate; 2-Oxo-6-(trifluoromethyl)-1,2-dihydropyridine-3-carboxylic acid methyl ester; 3-Methoxycarbonyl-6-(trifluoromethyl)-2(1H)-pyridinone
EINECS	Contact for details

Quality Control

Our Methyl 2-Oxo-6-(Trifluoromethyl)-1,2-Dihydropyridine-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency suitable for research and scale-up applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect product stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.