Description

2H-Pyrido[1,2-A]Pyrazine-7-Carboxylic Acid, Octahydro-1-Oxo-, Methyl Ester, (7R,9Ar)-Rel- is a high-purity, stereochemically defined heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key chiral intermediate for constructing complex molecular architectures, particularly in the pharmaceutical sector. It is primarily needed by research institutions and fine chemical manufacturers developing novel active pharmaceutical ingredients (APIs), agrochemicals, and other specialty chemicals where precise stereochemistry is critical for biological activity.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Synthesis: Used in the synthesis of advanced, stereoselective pesticides and herbicides where the specific stereochemistry can influence efficacy and environmental profile.
• Asymmetric Catalysis Research: Employed as a ligand precursor or a model substrate in the development of new asymmetric catalytic processes.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Academic & Industrial R&D: A valuable compound for methodological studies in synthetic organic chemistry, enabling novel ring-forming and functionalization reactions.

Basic Information

Item	Details
Product Name	2H-Pyrido[1,2-A]Pyrazine-7-Carboxylic Acid, Octahydro-1-Oxo-, Methyl Ester, (7R,9Ar)-Rel-
CAS No.	144731-64-6
Molecular Formula	C10H14N2O3
Molecular Weight	210.23 g/mol
Synonyms	rel-(7R,9aR)-Octahydro-1-oxo-2H-pyrido[1,2-a]pyrazine-7-carboxylic acid methyl ester; Methyl (7R,9aR)-octahydro-1-oxo-2H-pyrido[1,2-a]pyrazine-7-carboxylate; (7R,9aR)-Octahydro-1-oxo-2H-pyrido[1,2-a]pyrazine-7-carboxylic Acid Methyl Ester; 2H-Pyrido[1,2-a]pyrazine-7-carboxylic acid, octahydro-1-oxo-, methyl ester, (7R,9aR)-rel-; CAS 144731-64-6; Chiral Pyridopyrazine Ester; Octahydropyridopyrazinone Derivative.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material with a typical purity of ≥97% (by HPLC), with strict control over stereochemical purity and related substances. Certificates of Analysis (COA) detailing identity, assay, chiral purity, and impurity profiles are available upon request. Our quality management system supports cGMP standards for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Related Substances (HPLC)	Any single impurity ≤ 1.0%; Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.