Description

(5-Hydroxypentyloxy)-Acetic Acid tert-Butyl Ester is a valuable protected intermediate in organic synthesis, featuring both a hydroxyl group and a tert-butyl ester moiety. This bifunctional nature makes it a versatile building block for constructing complex molecules, particularly in pharmaceutical and fine chemical research. It is primarily sought after by R&D chemists and process development scientists for applications in medicinal chemistry and advanced material synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those requiring protected carboxylic acid and alcohol functionalities.
• Peptide Mimetics & Linker Chemistry: Used in the construction of peptide analogs and as a spacer or linker molecule in bioconjugation and prodrug development.
• Polymer & Material Science: Serves as a monomer or functional modifier in the synthesis of specialty polymers, coatings, and advanced materials.
• Agrochemical Synthesis: Intermediate in the production of novel herbicides, fungicides, and plant growth regulators.
• Liquid Crystal & Electronic Chemicals: Potential precursor for materials used in display technologies and organic electronics.
• Cross-Coupling Reactions: The protected ester group allows for further functionalization via various metal-catalyzed coupling methodologies.

Basic Information

Product Name	(5-Hydroxypentyloxy)-Acetic Acid tert-Butyl Ester
CAS No.	144682-02-0
Molecular Formula	C11H22O4
Molecular Weight	218.29 g/mol
Synonyms	tert-Butyl (5-hydroxypentyloxy)acetate; Acetic acid, 2-(5-hydroxypentyloxy)-, 1,1-dimethylethyl ester; 2-(5-Hydroxypentyloxy)acetic acid tert-butyl ester; 1,1-Dimethylethyl [2-(5-hydroxypentyloxy)]acetate; tert-Butyl 2-(5-hydroxypentoxy)acetate; 5-Hydroxypentyloxyacetic acid tert-butyl ester; TBHPOA ester
EINECS	Contact for details

Quality Control

Our (5-Hydroxypentyloxy)-Acetic Acid tert-Butyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to exclude moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.