Description

1,3-Dipalmitoyl-2-(4'-(Bis(2''-Chloroethyl)Amino)Phenylalaninoyl)Glycerol is a specialized synthetic phospholipid derivative designed for advanced research and development applications. This compound matters for its role as a key intermediate or functional component in the creation of targeted drug delivery systems, particularly in oncology and gene therapy. Pharmaceutical researchers, biotech companies, and advanced material scientists need this high-purity chemical for developing novel liposomal formulations and prodrugs.

Application

• Liposomal Drug Delivery: A critical phospholipid component for formulating stable, targeted liposomes for cancer therapeutics.
• Prodrug Synthesis: Serves as a sophisticated carrier molecule in the synthesis of prodrugs designed for selective activation.
• Bioconjugation & Targeting: Used to create ligand-targeted nanoparticles by attaching specific targeting moieties to the amino acid head group.
• Biomedical Research: A valuable tool in academic and industrial labs studying membrane biophysics, cellular uptake mechanisms, and intracellular trafficking.
• Contrast Agent Formulation: Potential use in the development of lipid-based carriers for diagnostic imaging agents.
• Gene Delivery Systems: Investigated as a component in non-viral vectors for the encapsulation and delivery of nucleic acids (DNA, RNA).

Basic Information

Product Name	1,3-Dipalmitoyl-2-(4'-(Bis(2''-Chloroethyl)Amino)Phenylalaninoyl)Glycerol
CAS No.	144558-52-1
Molecular Formula	C53H92Cl2N2O7
Molecular Weight	940.20 g/mol
Synonyms	1,3-Dipalmitoyl-2-[4-[bis(2-chloroethyl)amino]phenylalanyl]glycerol; Glycerol, 1,3-bis(hexadecanoyl)-2-[[4-[bis(2-chloroethyl)amino]phenyl]alanyl]-, (2S)-; 2-[[4-[Bis(2-chloroethyl)amino]phenyl]alanyl]-1,3-bis(hexadecanoyl)glycerol; Nitrogen Mustard Phenylalanine Glycerol Diester; Chlorambucil Glycerolipid Conjugate; Phospholipid-Mimetic Prodrug Intermediate; Targeted Lipid Prodrug Carrier
EINECS	Contact for details

Quality Control

Our 1,3-Dipalmitoyl-2-(4'-(Bis(2''-Chloroethyl)Amino)Phenylalaninoyl)Glycerol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with full traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) to minimize oxidation. Keep the container in a dry, cool, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.