Description

1,7-Diazaspiro[4.4]Nonane-2,6-Dione,8-Hydroxy-,(5R-Trans)-(9Ci) is a high-purity, stereochemically defined spirocyclic compound that serves as a critical advanced intermediate in modern organic synthesis. Its value lies in its unique fused ring structure and functional groups, which make it a versatile building block for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in areas requiring complex spirocyclic or heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the design and synthesis of novel herbicides, fungicides, and insecticides, leveraging its rigid molecular framework.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex natural product analogs and specialty chemicals.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or precursor for developing novel polymers with specific thermal or mechanical properties.

Basic Information

Product Name	1,7-Diazaspiro[4.4]Nonane-2,6-Dione,8-Hydroxy-,(5R-Trans)-(9Ci)
CAS No.	144466-57-9
Molecular Formula	C7H8N2O3
Molecular Weight	168.15 g/mol
Synonyms	(5R)-8-Hydroxy-1,7-diazaspiro[4.4]nonane-2,6-dione; 8-Hydroxy-1,7-diazaspiro[4.4]nonane-2,6-dione, (5R)-; (5R-trans)-8-Hydroxy-1,7-diazaspiro[4.4]nonane-2,6-dione; 144466-57-9; (5R)-8-Hydroxy-1,7-diazaspiro[4.4]nonane-2,6-dione; 1,7-Diazaspiro[4.4]nonane-2,6-dione, 8-hydroxy-, (5R-trans)-; SCHEMBL2184221; DTXSID90672966
EINECS	Contact for details

Quality Control

Our 1,7-Diazaspiro[4.4]Nonane-2,6-Dione,8-Hydroxy-,(5R-Trans)-(9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and production applications. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.