Description

(3α,7α,17α)-7-Methyl-19-Norpregn-5(10)-En-20-Yne-3,17-Diol 17-(Hydrogen Sulfate) CAS NO 144466-05-7 is a high-purity, synthetic steroid derivative, specifically a 19-nor pregnane sulfate ester. This compound is a critical pharmaceutical intermediate and a key building block in the synthesis of more complex therapeutic agents. It is primarily utilized by pharmaceutical R&D and fine chemical manufacturing sectors for the development of novel steroid-based drugs.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of advanced steroid-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for the discovery and development of new therapeutic agents targeting hormone receptors.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Process Chemistry: Employed in process development and scale-up for the commercial manufacturing of steroid drugs.
• Biochemical Research: Used in studies investigating steroid metabolism, enzyme inhibition, and receptor-ligand interactions.

Basic Information

Item	Detail
Product Name	(3α,7α,17α)-7-Methyl-19-Norpregn-5(10)-En-20-Yne-3,17-Diol 17-(Hydrogen Sulfate)
CAS No.	144466-05-7
Molecular Formula	C21H30O5S
Molecular Weight	394.53 g/mol
Synonyms	7α-Methyl-19-nor-17α-pregna-5(10)-en-20-yne-3β,17β-diol 17-sulfate; Tibolone Sulfate; 7α-Methyl-19-nortestosterone 17β-sulfate; Org OD-14 Sulfate; Livial Sulfate (Intermediate); 19-Norpregn-5(10)-en-20-yne-3,17-diol, 7-methyl-, 17-(hydrogen sulfate), (3β,7α,17α)-; 7α-Methyl-19-nor-17α-pregna-5(10)-en-20-yn-3β,17β-diol 17-sulfate
EINECS	Contact for details

Quality Control

Our (3α,7α,17α)-7-Methyl-19-Norpregn-5(10)-En-20-Yne-3,17-Diol 17-(Hydrogen Sulfate) is manufactured under strict quality systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.