Description

(E)-tert-Butyl 3-(4-Formylphenyl)Acrylate is a high-purity, versatile acrylate ester derivative featuring a formylphenyl group, making it a valuable building block in advanced organic synthesis. Its primary value lies in its dual functionality, serving as a key intermediate for constructing complex molecules in pharmaceutical and material science research. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty polymer industries who require reliable, high-quality intermediates for scale-up and production.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a cinnamate or styryl backbone.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators that incorporate acrylic acid derivatives.
• Polymer & Material Science: Serves as a functional monomer or cross-linking agent for creating specialty polymers with tailored properties like UV-absorption or specific reactivity.
• Organic Light-Emitting Diodes (OLEDs): Acts as a building block for electron-transport materials or emissive layer components in OLED device fabrication.
• Liquid Crystal & Display Technology: Employed in the synthesis of advanced liquid crystal molecules for display applications.
• Chemical Biology & Proteomics: Utilized as a scaffold or linker in the development of chemical probes and bioconjugation reagents.
• Fine Chemical Synthesis: A versatile reagent for constructing complex organic frameworks via reactions like Heck coupling, Michael addition, or cyclization.

Basic Information

Product Name	(E)-tert-Butyl 3-(4-Formylphenyl)Acrylate
CAS No.	144374-53-8
Molecular Formula	C14H16O3
Molecular Weight	232.28 g/mol
Synonyms	tert-Butyl (2E)-3-(4-formylphenyl)prop-2-enoate; 4-[(1E)-3-(tert-Butoxy)-3-oxo-1-propen-1-yl]benzaldehyde; (E)-3-(4-Formylphenyl)-2-propenoic acid tert-butyl ester; p-Formylcinnamic acid tert-butyl ester; (E)-tert-Butyl p-formylcinnamate; 4-(3-tert-Butoxycarbonyl-2-propenyl)benzaldehyde; Acrylic acid, 3-(4-formylphenyl)-, 1,1-dimethylethyl ester, (E)-; 144374-53-8
EINECS	Contact for details

Quality Control

Our (E)-tert-Butyl 3-(4-Formylphenyl)Acrylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your most demanding R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Isomeric Purity (E/Z Ratio)	≥ 99:1 (E/Z)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.