Description

Thiangazole CAS NO 144370-38-7 is a potent and specific synthetic antibiotic belonging to the thiazole class of compounds. This compound is valued for its targeted antimicrobial activity, making it a critical intermediate and reference standard in advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery of novel anti-infective agents and the study of microbial resistance mechanisms.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel antibiotic candidates.
• Biochemical Research: Used as a reference standard and probe compound in studies of bacterial enzyme inhibition and mechanism of action.
• Antimicrobial Development: A critical material for R&D programs focused on combating drug-resistant bacterial strains.
• Analytical Standard: Employed as a high-purity standard for quality control and method development in analytical laboratories (HPLC, LC-MS).
• Academic Research: Utilized in university and institutional labs for microbiological and pharmacological studies.

Basic Information

Product Name	Thiangazole
CAS No.	144370-38-7
Molecular Formula	C15H17N3O3S2
Molecular Weight	351.45 g/mol
Synonyms	Thiangazole; L-696,474; (2R,3S,4S)-2-(2-((2S,5S)-5-((S)-sec-Butyl)-2-thiazolyl)thiazol-4-yl)-3,4-dihydroxybutyramide; L696474; Antibiotic L 696474; L-696474
EINECS	Contact for details

Quality Control

Our Thiangazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and MS, and residual solvent analysis, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.