Description

2-Iodomethyl-Cyclopropane-1,1-Dicarboxylic Acid Diethyl Ester is a versatile and highly functionalized cyclopropane derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the reactive iodomethyl group and the protected dicarboxylic acid moiety, enabling complex molecular construction with high precision. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of cyclopropane-containing drug candidates, such as protease inhibitors and other biologically active molecules.
• Agrochemical Synthesis: Building block for developing novel pesticides and herbicides that leverage the strained cyclopropane ring for enhanced activity.
• Material Science Research: Used in the development of specialty polymers and advanced materials with unique structural properties.
• Organic Methodology Development: A valuable substrate for developing new cross-coupling reactions, cycloadditions, and other catalytic transformations in academic and industrial R&D.
• Ligand and Catalyst Preparation: Intermediate for synthesizing complex chiral ligands and organometallic catalysts used in asymmetric synthesis.

Basic Information

Product Name	2-Iodomethyl-Cyclopropane-1,1-Dicarboxylic Acid Diethyl Ester
CAS No.	144296-42-4
Molecular Formula	C10H15IO4
Molecular Weight	326.13 g/mol
Synonyms	Diethyl 2-(iodomethyl)-1,1-cyclopropanedicarboxylate; 1,1-Cyclopropanedicarboxylic acid, 2-(iodomethyl)-, diethyl ester; Diethyl (iodomethyl)cyclopropane-1,1-dicarboxylate; Ethyl 2-(iodomethyl)-1,1-cyclopropanedicarboxylate; (Iodomethyl)cyclopropane-1,1-dicarboxylic acid diethyl ester; 144296-42-4; Cyclopropane-1,1-dicarboxylic acid, 2-(iodomethyl)-, diethyl ester
EINECS	Contact for details

Quality Control

Our 2-Iodomethyl-Cyclopropane-1,1-Dicarboxylic Acid Diethyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and structural integrity. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality system supports cGMP and ISO standards for reliable, batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or opaque.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.