Description

5-Azaspiro[2.4]Heptan-7-Amine, 5-(Phenylmethyl)-, (S)- is a high-purity, chiral spirocyclic amine building block of significant interest in advanced organic synthesis. This compound matters for its unique three-dimensional structure and stereochemical integrity, which are critical for modulating the biological activity and physicochemical properties of novel molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, particularly in the synthesis of complex active pharmaceutical ingredients (APIs) and drug candidates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.
• Medicinal Chemistry: Used as a constrained scaffold to explore structure-activity relationships (SAR) and improve the metabolic stability and selectivity of lead compounds.
• Agrochemical Research: Serves as a building block for the synthesis of new pesticides and herbicides with potentially novel modes of action.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or ligand precursor in catalytic asymmetric transformations.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers with unique optical or electronic properties.

Basic Information

Product Name	5-Azaspiro[2.4]Heptan-7-Amine, 5-(Phenylmethyl)-, (S)-
CAS No.	144282-35-9
Molecular Formula	C13H18N2
Molecular Weight	202.30 g/mol
Synonyms	(S)-5-Benzyl-5-azaspiro[2.4]heptan-7-amine; (7S)-5-Benzyl-5-azaspiro[2.4]heptan-7-amine; (S)-5-Benzyl-5-azaspiro[2.4]heptan-7-ylamine; 5-Azaspiro[2.4]heptan-7-amine, 5-(phenylmethyl)-, (7S)-; (S)-5-(Phenylmethyl)-5-azaspiro[2.4]heptan-7-amine; (S)-5-Benzyl-5-azaspiro[2.4]heptan-7-amine hydrochloride (salt form); L-5-Benzyl-5-azaspiro[2.4]heptan-7-amine
EINECS	Contact for details

Quality Control

Our 5-Azaspiro[2.4]Heptan-7-Amine, 5-(Phenylmethyl)-, (S)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.