Description

4-([tert-Butyl(Dimethyl)Silyl]Oxy)-1-Penten-3-One is a specialized organosilicon-protected ketone intermediate of significant importance in advanced organic synthesis. Its core value lies in its role as a versatile building block, offering a protected hydroxyl equivalent that enables complex, multi-step reactions with high selectivity and yield. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, reliable intermediates for synthesizing complex target molecules.

Application

• Pharmaceutical Intermediate: A key protected synthon in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly for complex molecules requiring selective deprotection strategies.
• Agrochemical Synthesis: Used in the research and development of novel pesticides, herbicides, and fungicides where its silyl protecting group is crucial for achieving desired reactivity.
• Organic Synthesis Building Block: Serves as a versatile precursor in academic and industrial laboratories for constructing carbon chains and introducing functional groups in a controlled manner.
• Material Science Research: Employed in the development of specialty polymers, ligands, and organic electronic materials that require precise molecular architecture.
• Process Chemistry Development: Utilized in scaling up synthetic routes from laboratory to pilot plant and commercial production, where consistent quality is paramount.

Basic Information

Product Name	4-([tert-Butyl(Dimethyl)Silyl]Oxy)-1-Penten-3-One
CAS No.	144193-95-3
Molecular Formula	C11H22O2Si
Molecular Weight	214.38 g/mol
Synonyms	1-Penten-3-one, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-; 4-(tert-Butyldimethylsilyloxy)-1-penten-3-one; 4-(TBDMSO)-1-penten-3-one; 4-[(tert-Butyldimethylsilyl)oxy]pent-1-en-3-one; 4-OTBDMS-1-penten-3-one; 4-(tert-Butyl(dimethyl)silyloxy)pent-1-en-3-one
EINECS	Contact for details

Quality Control

Our production of 4-([tert-Butyl(Dimethyl)Silyl]Oxy)-1-Penten-3-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for your critical synthesis workflows. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to verify identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) detailing all test results are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.