Description

Carbamic Acid, (2-Fluoro-1,1-Dimethyl-2-Oxoethyl)-, 1,1-Dimethylethyl Ester is a specialized fluorinated carbamate ester building block of significant interest in advanced organic synthesis. Its value lies in providing a protected amine functionality and a reactive fluorinated ketone moiety, enabling the construction of complex molecular architectures. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of fluorinated drug candidates, particularly in protease inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and metabolic stability.
• Peptidomimetics & PROTACs: Serves as a versatile precursor for constructing peptide analogs and Proteolysis Targeting Chimeras (PROTACs) due to its carbamate and reactive carbonyl groups.
• Material Science Research: Employed in the synthesis of fluorinated polymers and specialty materials with unique surface properties and stability.
• Chemical Biology Probes: Utilized as a scaffold for creating fluorescent tags or activity-based probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific projects requiring high-purity, complex fluorinated intermediates.

Basic Information

Product Name	Carbamic Acid, (2-Fluoro-1,1-Dimethyl-2-Oxoethyl)-, 1,1-Dimethylethyl Ester
CAS No.	144168-04-7
Molecular Formula	C9H16FNO3
Molecular Weight	205.23 g/mol
Synonyms	tert-Butyl N-(2-fluoro-1,1-dimethyl-2-oxoethyl)carbamate; 2-[(tert-Butoxycarbonyl)amino]-2-fluoro-2-methylpropanoic Acid tert-Butyl Ester; 2-Fluoro-2-[(tert-butoxycarbonyl)amino]-2-methylpropanoic Acid tert-Butyl Ester; Boc-Amino(fluoro)dimethylacetic Acid tert-Butyl Ester; N-Boc-2-Amino-2-fluoro-2-methylpropionic Acid tert-Butyl Ester; (2-Fluoro-1,1-dimethyl-2-oxoethyl)carbamic Acid tert-Butyl Ester; 144168-04-7; tert-Butyl (2-fluoro-1,1-dimethyl-2-oxoethyl)carbamate
EINECS	Contact for details

Quality Control

Every batch of Carbamic Acid, (2-Fluoro-1,1-Dimethyl-2-Oxoethyl)-, 1,1-Dimethylethyl Ester is produced and analyzed under strict quality management protocols to ensure consistency and purity for sensitive synthetic applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing comprehensive analytical results from techniques including HPLC, NMR, and MS.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.