Description

n-(3-((4-Aminobutyl)(3-Aminopropyl)Amino)Propyl)-4-(Bis(2-Chloroethyl) Amino)Benzenebutanamide is a specialized, high-purity synthetic intermediate of significant interest in advanced pharmaceutical research and development. Its complex polyamine structure, featuring both chloroethyl and aminopropyl/butyl groups, makes it a valuable precursor for constructing targeted therapeutic agents. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel drug candidates, particularly in oncology and targeted therapy. Its precise synthesis and consistent quality are critical for ensuring reliable downstream results in complex chemical syntheses.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel, targeted anti-cancer agents and other specialized therapeutic molecules.
• Bioconjugation Chemistry: Used in the development of antibody-drug conjugates (ADCs) and other targeted drug delivery systems due to its reactive amine and chloroethyl functional groups.
• Research & Development: Serves as a critical reagent in academic and industrial R&D for exploring new chemical entities and biological pathways.
• Ligand Synthesis: Employed in the creation of complex chelating agents and ligands for diagnostic imaging or metal-based therapeutics.
• Polymer Modification: Can be used to introduce functional amine groups into polymers for specialized material science applications.

Basic Information

Product Name	n-(3-((4-Aminobutyl)(3-Aminopropyl)Amino)Propyl)-4-(Bis(2-Chloroethyl) Amino)Benzenebutanamide
CAS No.	143984-22-9
Molecular Formula	C24H43Cl2N5O
Molecular Weight	488.54 g/mol
Synonyms	4-[Bis(2-chloroethyl)amino]-N-[3-[[4-[(3-aminopropyl)amino]butyl](3-aminopropyl)amino]propyl]benzeneacetamide; 4-[Bis(2-chloroethyl)amino]-N-[3-[[4-[(3-aminopropyl)amino]butyl](3-aminopropyl)amino]propyl]benzenebutanamide; Spermidine-N-Chlorambucil Conjugate; Chlorambucil-Spermidine Conjugate; NSC-D 328243; UNII-2V1T2P0S8K; Spermidine-chlorambucil hybrid
EINECS	Contact for details

Quality Control

Our n-(3-((4-Aminobutyl)(3-Aminopropyl)Amino)Propyl)-4-(Bis(2-Chloroethyl) Amino)Benzenebutanamide is manufactured under strict quality management systems to ensure the high purity and consistency required for research and pharmaceutical applications. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the specific results for that lot. We adhere to cGMP principles where applicable to support our clients' regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area, away from incompatible materials. For long-term storage, consider freezing at -20°C under inert conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.