Description

Spiro[2.2]Pentane, 1-Chloro-1-Ethynyl- (9Ci) is a highly functionalized, strained spirocyclic compound that serves as a valuable and versatile building block in advanced organic synthesis. Its unique structure, featuring both a reactive chloro and ethynyl group on the same carbon atom, makes it a critical precursor for constructing complex molecular architectures. This specialty chemical is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting complex, three-dimensional scaffolds.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where its spirocyclic core can impart unique biological activity and stability.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced materials with tailored properties.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for cycloaddition reactions, cross-coupling, and other transformations to create complex, strained ring systems.
• Ligand and Catalyst Development: Utilized for the synthesis of novel chiral ligands or organometallic complexes used in asymmetric catalysis.

Basic Information

Product Name	Spiro[2.2]Pentane, 1-Chloro-1-Ethynyl- (9Ci)
CAS No.	143962-00-9
Molecular Formula	C7H5Cl
Molecular Weight	124.57 g/mol
Synonyms	1-Chloro-1-ethynylspiro[2.2]pentane; 1-Chloro-1-ethynylspiropentane; 1-Ethynyl-1-chlorospiro[2.2]pentane; Spiro[2.2]pentane, 1-chloro-1-ethynyl-; 1-Chloro-1-ethynylspiro(2.2)pentane
EINECS	Contact for details

Quality Control

Our production of Spiro[2.2]Pentane, 1-Chloro-1-Ethynyl- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes comprehensive analytical characterization, including NMR, GC, and HPLC analysis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Recommended storage temperature is between 2°C and 8°C (refrigerated) for long-term stability, as the compound is light-sensitive. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.