Description

3-Pyrrolidinecarboxylicacid,2-Methyl-,Methylester,(2S-Cis)-(9Ci) is a high-value, stereochemically defined chiral building block and intermediate. This compound matters for its role in the synthesis of complex molecules, particularly in pharmaceutical research and development where specific stereochemistry is critical for biological activity. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder therapeutics.
• Agrochemical Synthesis: Used in the creation of advanced, stereoselective pesticides and herbicides where the specific (2S-cis) configuration can enhance efficacy and reduce environmental impact.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to induce high enantioselectivity in chemical reactions.
• Peptidomimetics Research: Employed in the design and synthesis of peptidomimetics and conformationally restricted amino acid analogs for drug discovery programs.
• Fine Chemical Production: Acts as a specialized intermediate in custom synthesis and contract manufacturing for high-value, low-volume specialty chemicals.
• Academic & R&D Laboratories: Utilized in university and institutional research for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	3-Pyrrolidinecarboxylicacid,2-Methyl-,Methylester,(2S-Cis)-(9Ci)
CAS No.	143878-87-9
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	(2S,3S)-2-Methyl-3-pyrrolidinecarboxylic acid methyl ester; Methyl (2S,3S)-2-methylpyrrolidine-3-carboxylate; (2S,3S)-2-Methylpyrrolidine-3-carboxylic acid methyl ester; L-threo-2-Methyl-3-pyrrolidinecarboxylic acid methyl ester; (3S,4S)-4-Methyl-3-pyrrolidinecarboxylic acid methyl ester; (2S-cis)-2-Methyl-3-pyrrolidinecarboxylic acid methyl ester; 3-Pyrrolidinecarboxylic acid, 2-methyl-, methyl ester, (2S-cis)-
EINECS	Contact for details

Quality Control

Our 3-Pyrrolidinecarboxylicacid,2-Methyl-,Methylester,(2S-Cis)-(9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided and available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Enantiomeric Excess)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.