Description

Carbamic Acid, (1-Oxo-3-Phenyl-2-Propenyl)-, Ethyl Ester, (E)- (9Ci) is a specialized organic compound belonging to the class of carbamate esters. This molecule is significant as a versatile synthetic intermediate, particularly valued for its α,β-unsaturated ketone (enone) moiety conjugated with a carbamate functional group. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical sectors for constructing complex molecular architectures, such as in the synthesis of potential bioactive molecules and heterocyclic compounds. Its defined stereochemistry (E-isomer) ensures consistent reactivity and predictable outcomes in synthetic pathways.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the research and synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring a functionalized cinnamoyl scaffold.
• Agrochemical Research: Used in developing new candidates for herbicides, fungicides, and insecticides, leveraging its reactive sites for structural diversification.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for Michael addition reactions, cyclization processes, and as a precursor to various heterocycles like pyrazoles and pyrimidines.
• Material Science Research: Investigated as a monomer or cross-linking agent in the development of specialty polymers with tailored properties.
• Chemical Biology Probe Development: Utilized in designing molecular probes to study enzyme activity or biological pathways due to its electrophilic carbonyl group.

Basic Information

Product Name	Carbamic Acid, (1-Oxo-3-Phenyl-2-Propenyl)-, Ethyl Ester, (E)- (9Ci)
CAS No.	143816-12-0
Molecular Formula	C12H13NO3
Molecular Weight	219.24 g/mol
Synonyms	(E)-Ethyl (3-phenylacryloyl)carbamate; Ethyl (E)-3-phenyl-2-propenoyl carbamate; (E)-Ethyl 3-phenylprop-2-enoylcarbamate; trans-Ethyl cinnamoylcarbamate; N-Carbethoxycinnamamide; Carbamic acid, N-(3-phenyl-2-propenoyl)-, ethyl ester, (E)-; Ethyl N-cinnamoylcarbamate (E-isomer)
EINECS	Contact for details

Quality Control

Our production of Carbamic Acid, (1-Oxo-3-Phenyl-2-Propenyl)-, Ethyl Ester, (E)- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.