Description

(2R,4R)-3-Benzyloxycarbonyl-4-Methyl-2-Phenyl-1,3-Oxazolidin-5-One is a high-purity chiral oxazolidinone derivative, a critical building block in asymmetric synthesis. Its value lies in its role as a versatile chiral auxiliary and intermediate for constructing complex, stereochemically defined molecules, ensuring high enantiomeric purity in final products. This compound is essential for research and development chemists in the pharmaceutical and fine chemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and advanced agrochemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Chiral Auxiliary: Used to control stereoselectivity in aldol, alkylation, and other carbon-carbon bond-forming reactions.
• Fine Chemical Synthesis: Employed in the research and production of specialty chemicals requiring high enantiomeric excess.
• Agrochemical Development: Serves as a building block for creating chiral pesticides and herbicides with improved efficacy and environmental profiles.
• Academic & Industrial R&D: A valuable tool for methodological development in organic and medicinal chemistry laboratories.
• Peptidomimetics & Bioactive Molecule Construction: Facilitates the synthesis of non-natural amino acid derivatives and other bioactive scaffolds.

Basic Information

Product Name	(2R,4R)-3-Benzyloxycarbonyl-4-Methyl-2-Phenyl-1,3-Oxazolidin-5-One
CAS No.	143564-89-0
Molecular Formula	C18H17NO4
Molecular Weight	311.33 g/mol
Synonyms	(2R,4R)-4-Methyl-2-phenyl-3-[(phenylmethoxy)carbonyl]-1,3-oxazolidin-5-one; (2R,4R)-3-(Benzyloxycarbonyl)-4-methyl-2-phenyl-5-oxazolidinone; (2R,4R)-3-(Cbz)-4-methyl-2-phenyl-1,3-oxazolidin-5-one; (2R,4R)-Cbz-4-Methyl-2-phenyloxazolidin-5-one; (2R,4R)-3-Carbobenzoxy-4-methyl-2-phenyl-5-oxazolidinone; (2R,4R)-3-(Benzyloxycarbonyl)-4-methyl-2-phenyloxazolidin-5-one; (2R,4R)-4-Methyl-2-phenyl-3-[(benzyloxy)carbonyl]-1,3-oxazolidin-5-one
EINECS	Contact for details

Quality Control

Our (2R,4R)-3-Benzyloxycarbonyl-4-Methyl-2-Phenyl-1,3-Oxazolidin-5-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and standard spectroscopic methods for identity confirmation, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, chiral excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.