Description

Coalpha-(α-5,6-Dimethylbenzimidazolyl)-Cobeta-Cyanocobamide is a sophisticated, organometallic compound belonging to the cobalamin (vitamin B12) family. This high-purity intermediate is critical for ensuring the biological activity and stability of final pharmaceutical and nutraceutical products. It is primarily required by manufacturers in the pharmaceutical, advanced biochemical synthesis, and high-grade nutritional supplement industries for the production of active pharmaceutical ingredients (APIs) and premium vitamin formulations.

Application

• Pharmaceutical Active Ingredient (API) Synthesis: A key intermediate in the manufacturing of various therapeutic cobalamin derivatives and vitamin B12-based medications.
• Advanced Biochemical Research: Used as a high-purity standard and reagent in enzymatic studies, metabolic pathway research, and cofactor investigations.
• Nutraceutical and Vitamin Fortification: Serves as a premium-grade source for formulating high-potency dietary supplements, infant nutrition, and medical nutrition products.
• Cell Culture Media: Employed as a growth factor and essential nutrient in specialized cell culture applications and fermentation processes.
• Diagnostic Reagent Manufacturing: Utilized in the production of assay kits, calibration standards, and other in-vitro diagnostic components.

Basic Information

Product Name	Coalpha-(α-5,6-Dimethylbenzimidazolyl)-Cobeta-Cyanocobamide
CAS No.	143481-69-0
Molecular Formula	C72H100CoN18O17P
Molecular Weight	Approx. 1579.6 g/mol
Synonyms	Vitamin B12 Intermediate; Cobamide, cyano-; Coα-[α-(5,6-dimethylbenzimidazolyl)]-Coβ-cyanocobamide; Cyanocobalamin Impurity; Cobalamin Precursor; 5,6-Dimethylbenzimidazolyl cyanocobamide; Coα-(α-5,6-DMBZ)-Coβ-CNCbl; B12 Complex Intermediate
EINECS	Contact for details

Quality Control

Our Coalpha-(α-5,6-Dimethylbenzimidazolyl)-Cobeta-Cyanocobamide is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Production can be aligned with cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccated environment after opening to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	Dark red crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (UV-Vis)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.