Description

Ethanone, 1-[2-(Trimethylsilyl)-1-Cyclobuten-1-Yl]- (9Ci) is a specialized organosilicon building block featuring a unique cyclobutenone core functionalized with a trimethylsilyl group. This compound matters as a high-value synthetic intermediate, enabling the construction of complex molecular architectures through its reactive ketone and strained alkene functionalities. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and advanced materials sectors for applications in medicinal chemistry and organic synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for constructing complex carbocyclic and heterocyclic ring systems.
• Organic Synthesis Building Block: Utilized in [4+2] cycloaddition (Diels-Alder) reactions and other pericyclic transformations, leveraging the strain energy of the cyclobutene ring.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials with tailored properties.
• Agrochemical Synthesis: Employed in the research and development of new crop protection agents and herbicides.
• Ligand and Catalyst Development: Used to create novel organometallic complexes and chiral auxiliaries for asymmetric catalysis.
• Academic and Industrial R&D: A valuable reagent for methodological studies in organic chemistry and exploring new reaction pathways.

Basic Information

Product Name	Ethanone, 1-[2-(Trimethylsilyl)-1-Cyclobuten-1-Yl]- (9Ci)
CAS No.	143370-56-3
Molecular Formula	C9H16OSi
Molecular Weight	168.31 g/mol
Synonyms	1-[2-(Trimethylsilyl)-1-cyclobuten-1-yl]ethanone; 2-(Trimethylsilyl)cyclobut-1-ene-1-carbaldehyde?; 1-(2-Trimethylsilylcyclobuten-1-yl)ethanone; TMS-Cyclobutenone; (2-Trimethylsilylcyclobut-1-en-1-yl)methyl ketone; 2-Trimethylsilyl-1-cyclobuten-1-yl methyl ketone; Cyclobutenone, 2-(trimethylsilyl)-, methyl derivative
EINECS	Contact for details

Quality Control

Our Ethanone, 1-[2-(Trimethylsilyl)-1-Cyclobuten-1-Yl]- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, GC, and HPLC, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥95.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.