Description

(α2R,α6R)-α2,α6-Dimethyl-2,6-Pyridinedimethanol CAS NO 143329-86-6 is a high-purity, stereochemically defined chiral pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its rigid, symmetrical structure and dual hydroxymethyl functionality, which are essential for constructing complex molecular architectures with precise spatial orientation. This compound is primarily needed by research institutions and pharmaceutical development teams working on novel active pharmaceutical ingredients (APIs), asymmetric catalysts, and specialized ligands.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) targets.
• Asymmetric Catalyst Ligand: Used in the preparation of chiral ligands for transition metal catalysis, enabling enantioselective synthesis.
• Advanced Material Precursor: Employed in the synthesis of functionalized polymers and liquid crystals where molecular symmetry is crucial.
• Chemical Biology Probe: Serves as a scaffold for developing molecular probes to study enzyme mechanisms and receptor interactions.
• Academic & Industrial R&D: Fundamental building block in methodological chemistry research for constructing complex heterocyclic systems.

Basic Information

Product Name	(α2R,α6R)-α2,α6-Dimethyl-2,6-Pyridinedimethanol
CAS No.	143329-86-6
Molecular Formula	C9H13NO2
Molecular Weight	167.21 g/mol
Synonyms	(2R,6R)-2,6-Dimethyl-2,6-pyridinedimethanol; (2R,6R)-2,6-Bis(hydroxymethyl)-2,6-dimethylpyridine; (R,R)-2,6-Dimethylpyridine-2,6-diyldimethanol; 2,6-Pyridinedimethanol, 2,6-dimethyl-, (2R,6R)-; Chiral 2,6-Dimethylpyridinedimethanol; (R,R)-HMPD; (2R,6R)-HMPD
EINECS	Contact for details

Quality Control

Every batch of (α2R,α6R)-α2,α6-Dimethyl-2,6-Pyridinedimethanol is produced under strict quality management protocols to ensure exceptional chiral purity and chemical integrity. Our products undergo rigorous analytical testing, including chiral HPLC and NMR, to confirm identity, enantiomeric excess, and purity levels suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to exclude moisture. For long-term storage, consider the use of desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.