Description

(R)-Methyl 1-Benzyl-5-Oxopyrrolidine-2-Carboxylate is a high-purity chiral intermediate of significant importance in advanced organic synthesis. This compound matters because it serves as a critical building block for the development of novel pharmaceuticals and bioactive molecules, particularly those targeting neurological and metabolic pathways. Pharmaceutical R&D teams and fine chemical manufacturers need this enantiomerically pure material to synthesize complex active pharmaceutical ingredients (APIs) and explore new therapeutic candidates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Asymmetric Synthesis: Used as a starting material or advanced intermediate in stereoselective reactions to construct complex molecular architectures.
• Protease Inhibitor Research: Serves as a core scaffold for the development of inhibitors targeting specific enzymes like prolyl oligopeptidase.
• Nootropic & Cognitive Enhancer Precursor: Employed in the research and development of compounds aimed at improving cognitive function.
• Chemical Biology & Probe Development: Utilized to create molecular probes for studying biological pathways and protein functions.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry laboratories.

Basic Information

Product Name	(R)-Methyl 1-Benzyl-5-Oxopyrrolidine-2-Carboxylate
CAS No.	143317-59-3
Molecular Formula	C14H17NO3
Molecular Weight	247.29 g/mol
Synonyms	(R)-1-Benzyl-5-oxopyrrolidine-2-carboxylic acid methyl ester; Methyl (R)-1-benzyl-5-oxo-2-pyrrolidinecarboxylate; (R)-1-Benzylpyrrolidine-2,5-dione-2-carboxylic acid methyl ester; (R)-Methyl 1-benzyl-5-oxo-2-pyrrolidinecarboxylate; (2R)-1-Benzyl-5-oxopyrrolidine-2-carboxylic acid methyl ester; (R)-1-Benzyl-5-oxo-pyrrolidine-2-carboxylic acid methyl ester; (R)-1-Benzyl-2-(methoxycarbonyl)-5-pyrrolidinone
EINECS	Contact for details

Quality Control

Our (R)-Methyl 1-Benzyl-5-Oxopyrrolidine-2-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. The product undergoes rigorous analytical testing, including chiral HPLC, to meet the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with each batch.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.