Description

3-(1,4-Dioxaspiro[4.5]Dec-7-En-8-Yl)-1H-Indole is a specialized heterocyclic building block featuring a fused indole and spirocyclic ketal structure. This compound is valued for its unique molecular architecture, which serves as a critical intermediate in the synthesis of complex organic molecules, particularly in pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for constructing novel chemical entities with potential biological activity.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the discovery and production of advanced crop protection agents and pesticides.
• Material Science Research: Serves as a precursor for developing novel organic electronic materials or functional polymers.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in organic synthesis and heterocyclic chemistry.
• Fine Chemical Production: Integral to the multi-step synthesis of complex fragrance or flavor ingredients.

Basic Information

Product Name	3-(1,4-Dioxaspiro[4.5]Dec-7-En-8-Yl)-1H-Indole
CAS No.	143165-32-6
Molecular Formula	C₁₇H₁₉NO₂
Molecular Weight	269.34 g/mol
Synonyms	3-(1,4-Dioxaspiro[4.5]dec-7-en-8-yl)-1H-indole; 1H-Indole, 3-(1,4-dioxaspiro[4.5]dec-7-en-8-yl)-; 3-(1,4-Dioxaspiro[4.5]dec-7-en-8-yl)indole; 3-(8,9-Dihydro-2H,7H-spiro[1,3]dioxolo[4,5-g]isoquinolin-7-yl)-1H-indole; Spiro[indole-3,4'-piperidine] derivative
EINECS	Contact for details

Quality Control

Every batch of 3-(1,4-Dioxaspiro[4.5]Dec-7-En-8-Yl)-1H-Indole is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard research-grade material typically meets high-purity specifications suitable for advanced synthetic applications. A detailed Certificate of Analysis (COA) documenting purity (HPLC/GC), identity (IR, NMR), and impurity profile is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.