Description

Benzene, 1-Ethoxy-4-(1-Isocyanato-3-Butenyl)-, (R)- (9Ci) CAS NO 142935-67-9 is a specialized chiral isocyanate derivative of benzene, characterized by its reactive isocyanate (-NCO) and alkenyl functional groups. This compound is a high-value chemical building block for synthesizing advanced materials and pharmaceuticals, where its stereochemistry and dual functionality are critical. It is primarily required by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and CNS drug discovery.
• Agrochemical Synthesis: Used in the research and development of advanced, stereospecific herbicides, fungicides, and plant growth regulators.
• Polymer Crosslinking Agent: Serves as a reactive monomer in the production of specialty polyurethanes, coatings, and adhesives with tailored properties.
• Liquid Crystal & OLED Material Precursor: Employed in the synthesis of advanced organic electronic materials due to its benzene core and functional handles.
• Chiral Ligand & Catalyst Development: Acts as a foundational structure for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Bioconjugation & Probe Chemistry: Utilized in life sciences research for labeling biomolecules via its reactive isocyanate group.

Basic Information

Item	Details
Product Name	Benzene, 1-Ethoxy-4-(1-Isocyanato-3-Butenyl)-, (R)- (9Ci)
CAS No.	142935-67-9
Molecular Formula	C13H15NO2
Molecular Weight	217.26 g/mol
Synonyms	(R)-1-Ethoxy-4-(1-Isocyanato-3-butenyl)benzene; 4-Ethoxy-(R)-α-vinylbenzyl isocyanate; 1-Isocyanato-3-butenyl-4-ethoxybenzene, (R)-; p-Ethoxy-(R)-α-vinylbenzyl isocyanate; (R)-4-(1-Isocyanato-3-butenyl)phenetole; (R)-1-Ethoxy-4-(3-buten-1-ylisocyanato)benzene; Benzene, 1-ethoxy-4-[(1R)-1-isocyanato-3-buten-1-yl]-; (R)-α-Vinyl-4-ethoxybenzyl isocyanate
EINECS	Contact for details

Quality Control

Our Benzene, 1-Ethoxy-4-(1-Isocyanato-3-Butenyl)-, (R)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing including chiral purity analysis, assay, and impurity profiling to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided for every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation and polymerization. Keep away from heat, sparks, open flames, and incompatible materials such as alcohols, amines, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.1%
Isocyanate Content (Titration)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.