Description

3-Pyridinecarboxylicacid,6-(Acetylamino)-1,2,5,6-Tetrahydro-5-Hydroxy-,(5S-Trans)-(9Ci) is a high-purity, stereochemically defined advanced pharmaceutical intermediate. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) due to its specific pyridine-based scaffold and functional groups. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly in areas requiring chiral specificity and molecular complexity.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of proprietary drug candidates and complex APIs.
• Chemical Research & Development: Used as a precursor for novel heterocyclic compounds in medicinal chemistry and process development.
• Chiral Synthesis: Serves as a stereochemically pure starting material for the production of enantiomerically specific molecules.
• Biochemical Research: Potential use as a ligand or inhibitor in biochemical assays and enzyme studies.
• Academic Research: Employed in university and institutional labs for synthetic methodology development and structure-activity relationship (SAR) studies.

Basic Information

Product Name	3-Pyridinecarboxylicacid,6-(Acetylamino)-1,2,5,6-Tetrahydro-5-Hydroxy-,(5S-Trans)-(9Ci)
CAS No.	142779-94-0
Molecular Formula	C9H14N2O4
Molecular Weight	214.22 g/mol
Synonyms	(5S)-6-Acetamido-5-hydroxy-1,2,3,6-tetrahydropyridine-3-carboxylic acid; 6-Acetylamino-5-hydroxy-1,2,5,6-tetrahydro-3-pyridinecarboxylic acid (5S-trans); 5-Hydroxy-6-acetamido-1,2,3,6-tetrahydropyridine-3-carboxylic acid; (5S,6R)-6-Acetamido-5-hydroxy-3,6-dihydro-2H-pyridine-3-carboxylic acid; 142779-94-0; 3-Pyridinecarboxylic acid, 6-(acetylamino)-1,2,5,6-tetrahydro-5-hydroxy-, (5S-trans)-
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for pharmaceutical intermediates. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and stereochemical integrity. Certificates of Analysis (COA) are available upon request, detailing all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.