Description

Acetic Acid, [[(1,1-Dimethylethoxy)Carbonyl]Amino](Dimethoxyphosphinyl)-, Ethyl Ester is a specialized organophosphorus compound that serves as a high-value building block in advanced synthetic chemistry. Its molecular architecture, featuring both a Boc-protected amino group and a phosphinyl ester moiety, makes it a critical reagent for the controlled introduction of phosphorus-containing functional groups. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients, such as enzyme inhibitors and prodrugs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting phosphonate-based protease inhibitors.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and plant growth regulators with phosphonate backbones.
• Peptide Mimetics: Employed in the creation of phosphonopeptide analogs for studying enzyme mechanisms and developing therapeutic agents.
• Ligand & Catalyst Development: Serves as a precursor for chiral phosphine-phosphonate ligands used in asymmetric catalysis.
• Chemical Biology Probes: Utilized to synthesize activity-based probes for studying phosphorylation-dependent biological pathways.
• Material Science: Intermediate for the synthesis of specialty monomers intended for flame-retardant or metal-chelating polymers.

Basic Information

Product Name	Acetic Acid, [[(1,1-Dimethylethoxy)Carbonyl]Amino](Dimethoxyphosphinyl)-, Ethyl Ester
CAS No.	142602-46-8
Molecular Formula	C11H22NO7P
Molecular Weight	311.27 g/mol
Synonyms	Ethyl (Boc-amino)(dimethoxyphosphinyl)acetate; (Boc-Amino)(dimethoxyphosphoryl)acetic Acid Ethyl Ester; N-(tert-Butoxycarbonyl)-P,P-dimethoxyphosphonoglycine Ethyl Ester; (Dimethoxyphosphinyl)-N-[(1,1-dimethylethoxy)carbonyl]glycine Ethyl Ester; Glycine, N-[(1,1-dimethylethoxy)carbonyl]-, ethyl ester, P,P-dimethyl phosphonate; Boc-PO(OMe)2-Gly-OEt; Boc-NH-CH(PO(OMe)2)-COOEt
EINECS	Contact for details

Quality Control

Every batch of Acetic Acid, [[(1,1-Dimethylethoxy)Carbonyl]Amino](Dimethoxyphosphinyl)-, Ethyl Ester is produced and tested under strict quality management systems to ensure consistency and purity for critical R&D and scale-up applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.