Description

Methyl 2-Amino-2-(4-tert-Butylphenyl)Acetate Hydrochloride is a high-purity, pharmaceutically relevant intermediate in the form of a stable hydrochloride salt. This compound is a critical building block in the synthesis of complex molecules, offering a protected amino acid ester functionality essential for peptide coupling and chiral synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of active ingredients and fine chemicals. Its defined structure and purity are vital for ensuring reproducibility and efficacy in downstream synthetic processes.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and production of novel Active Pharmaceutical Ingredients (APIs), particularly in therapeutic areas requiring specific stereochemistry.
• Peptidomimetic Synthesis: Serves as a protected amino acid derivative for constructing peptide analogs and mimetics in drug discovery programs.
• Agrochemical Research: Used as a precursor in the development of advanced herbicides, fungicides, and plant growth regulators with targeted activity.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes, enzyme inhibitors, and labeled compounds for biochemical studies.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom chemical synthesis services catering to R&D and pilot-scale production.
• Academic Research: Utilized in university and institutional laboratories for methodological development in organic and medicinal chemistry.

Basic Information

Item	Detail
Product Name	Methyl 2-Amino-2-(4-tert-Butylphenyl)Acetate Hydrochloride
CAS No.	142524-46-7
Molecular Formula	C13H20ClNO2
Molecular Weight	257.76 g/mol
Synonyms	Methyl 2-amino-2-(4-tert-butylphenyl)acetate hydrochloride; Methyl (4-tert-butylphenyl)glycinate hydrochloride; 2-Amino-2-(4-tert-butylphenyl)acetic acid methyl ester hydrochloride; (4-tert-Butylphenyl)glycine methyl ester hydrochloride; Methyl α-amino-4-tert-butylbenzeneacetate hydrochloride; Methyl DL-2-amino-2-(4-tert-butylphenyl)acetate hydrochloride; (RS)-Methyl 2-amino-2-(4-tert-butylphenyl)acetate hydrochloride
EINECS	Contact for details

Quality Control

Our Methyl 2-Amino-2-(4-tert-Butylphenyl)Acetate Hydrochloride is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, enantiomeric excess (if applicable), and impurity profiles. We support compliance with cGMP and ISO guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed after each use to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.