Description

7-(4-Carboxybutanamido)Cephalosporin Mustard is a key chemical intermediate in the synthesis of advanced cephalosporin antibiotic conjugates. This compound is critical for researchers and manufacturers developing targeted antibiotic therapies, particularly antibody-drug conjugates (ADCs) for oncology applications. It is primarily utilized by pharmaceutical R&D teams, fine chemical suppliers, and contract manufacturing organizations (CMOs) focused on innovative antibiotic and bioconjugation platforms.

Application

• Antibody-Drug Conjugate (ADC) Payload Synthesis: Serves as a specialized linker-payload component for constructing targeted cephalosporin-based ADCs.
• Pharmaceutical Intermediate: A crucial building block in the research and production of novel third-generation cephalosporin antibiotics.
• Bioconjugation Research: Used in academic and industrial labs to develop new drug-antibody or drug-polymer conjugates.
• Prodrug Development: Employed in the design of prodrugs that release active cephalosporin moieties under specific physiological conditions.
• Chemical Biology Tool: Acts as a reagent for studying bacterial cell wall synthesis and enzyme inhibition mechanisms.

Basic Information

Product Name	7-(4-Carboxybutanamido)Cephalosporin Mustard
CAS No.	142478-50-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	7-[(4-Carboxybutanoyl)amino]cephalosporanic acid mustard; Cephalosporin C-7 mustard derivative; ADC Linker for Cephalosporins; 7-ACA Mustard derivative; Cephalosporin Mustard Intermediate; 7β-(4-Carboxybutanamido)cephalosporanic acid derivative; Antibiotic conjugate intermediate
EINECS	Contact for details

Quality Control

Our 7-(4-Carboxybutanamido)Cephalosporin Mustard is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.